Saved as a Tiff, all of the attributes from the scanning process are retained, allowing further image processing later without loss of detail or definition. This format is recommended if you intend to do a lot of editing later, or if you require higher colour resolution. Tiff format files can be scanned and saved as 8-bit (24-bit colour resolution) or 16-bit (48-bit colour resolution). A 16-bit scan can be reduced to 8-bit, but not vice versa. For most practical purposes 16 bit scanning does not produce significantly visible differences, it can produce much finer steps in gradual colour changes and can allow very specific colour tone settings.

File sizes are approximately as follows, and depend upon the amount of cropping needed, CMYK files are about 35% larger:

35mm
  8-bit RGB 16-bit RGB Pixels  
1350 7.5MB 15MB 1940 x 1290  
2700 30MB 60MB 3880 x 2590  
4000 66MB 133MB 5780 x 3940  
6 x 4.5 cm (120 half frame / 645 format)
  8-bit RGB 16-bit RGB Pixels  
1350 15MB 30MB 3025 x 2260  
2700 65MB 130MB 6050 x 4520  
4000 170MB 340MB 8960 x 6690  
6 x 6 cm (120 square format)
  8-bit RGB 16-bit RGB Pixels  
1350 20MB 40MB 3025 x 3025  
2700 80MB 160MB 6050 x 6050  
4000 230MB 460MB 8960 x 8960  
6 x 7 cm
  8-bit RGB 16-bit RGB Pixels  
1350 24MB 48MB 3025 x 3720  
2700 96MB 192MB 6050 x 7440  
4000 280MB 560MB 8960 x 11015  
6 x 8 cm
  8-bit RGB 16-bit RGB Pixels  
1350 27MB 54MB 3025 x 4120  
2700 108MB 216MB 6050 x 8240  
4000 315MB 630MB 8960 x 12200  
6 x 9 cm (120 Full Frame)
  8-bit RGB 16-bit RGB Pixels  
1350 29MB 58MB 3025 x 4450  
2700 116MB 232MB 6050 x 8900  
4000 340MB 680MB 8960 x 13175